Depression, a disease of the mind? Actually our immune system could be the culprit

This makes sense. Managing allergies is tricky. Too much or little of anything can upset the apple cart and cause an allergic reaction of varying proportions. Here is another article along this vein that might interesting readers titled “BRAIN ALLERGIES:How Sensitivities to Food and Other Substances Can Effect the Mind.” Click here or on the pdf file to read the full article or an excerpt below.


So if the inflammation is causing the depression — possibly by producing chemicals that interfere with the production of serotonin — what is causing the inflammation? There are a number of possibilities.

Inflammation is the body’s response to infection but it can be triggered by stress and exacerbated by an unhealthy lifestyle.

There is also some research suggesting that children exposed to high levels of infection or to severe stressors such as traumatic life events are more likely to suffer from depression as adults.

Carmine Pariante, professor of biological psychiatry at King’s College, London, says: ‘With these individuals, the exposure to stress early in life modifies the functioning of the inflammatory system — it sets it to a higher sensitivity if you like. When these people encounter stressful life events later in life, the inflammatory system over-reacts and precipitates the depressive episode.’

And people who have never experienced depression probably do know something of what it feels like. Flu or a bad cold often begins with a period of appetite loss, listlessness, an ability to focus and a lack of interest in anything other than hugging the sofa. This is because the body reacts to the infection with inflammation, which in turn causes these mood changes.




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